As the aroma of melty cheese fills the kitchen, my heart races in anticipation—dinner is about to become an exciting adventure! These Cheesy Pepperoni Pizza Roll-Ups are not just your average snack; they’re a fun, low-carb twist on a beloved classic that the whole family will adore. Wrapped in a soft, low-carb tortilla, each roll-up is a delightful treasure packed with gooey mozzarella, crispy pepperoni, and zesty tomato sauce. The beauty of this recipe lies in its versatility—whether you’re prepping for a game night or looking for a quick lunch, they’re perfect for any occasion. Plus, they’re super easy to make, so you won’t be spending hours in the kitchen! Are you ready to roll up your sleeves and dive into a delicious slice of pizza-inspired goodness?

Why are these roll-ups a must-try?
Convenience: These Cheesy Pepperoni Pizza Roll-Ups come together in just 30 minutes, making them a perfect quick meal solution for busy days.
Crowd-Pleasing: Kids and adults alike will rave about these savory snacks, making them ideal for game nights or casual get-togethers.
Low-Carb Alternative: Satisfy your pizza cravings without the guilt, perfectly tailored for low-carb lovers!
Versatile Options: Swap out pepperoni for your favorite toppings or sauces; the possibilities are endless! If you’re looking for more ideas, check out these Pepperoni Pizza Bombs or Pepperoni Pizzadillas Pizza.
Deliciously Melty: With gooey mozzarella and a crispy exterior, each bite is a delightful flavor explosion!
Make-Ahead Ease: Prep some roll-ups ahead of time and have a delicious snack ready to go whenever you need a quick bite.
Cheesy Pepperoni Pizza Roll-Ups Ingredients
Get ready to gather your kitchen essentials for this scrumptious low-carb delight!
For the Roll-Ups
- Low-Carb Tortillas – The base of the roll-up that provides structure; you can substitute with keto-friendly wraps if desired.
- Shredded Mozzarella Cheese – Adds creaminess and flavor; swap for cheddar or a dairy-free cheese for a vegan option.
- Pepperoni Slices – The main protein source giving a savory kick; alternatives include cooked sausage or bacon for variation.
- Tomato Sauce – Moistens and flavors the roll-up; use homemade marinara or barbecue sauce for a unique twist.
For the Seasoning
- Italian Seasoning – Infuses an Italian herb medley for flavor enhancement; fresh herbs can bring a fresher taste.
- Garlic Powder – Offers aromatic depth; use fresh minced garlic for a stronger flavor.
Optional Enhancements
- Parmesan Cheese – For extra richness, sprinkle some on top before baking.
- Olives – Add briny notes, and diced for added flavor.
- Bell Peppers – Great for boosting nutrients and adding freshness; slice thinly for the best results.
Step‑by‑Step Instructions for Cheesy Pepperoni Pizza Roll-Ups
Step 1: Preheat the Oven
Start by preheating your oven to 375°F (190°C). This prepares the perfect environment for your Cheesy Pepperoni Pizza Roll-Ups to bake evenly. While it warms up, line a baking sheet with parchment paper for easier cleanup and to prevent sticking.
Step 2: Prepare the Tortilla
Once the oven is ready, lay out a low-carb tortilla on a clean surface. Spread a generous layer of zesty tomato sauce over the tortilla, leaving about an inch around the edges for easy rolling. You’ll want the sauce to provide moisture and flavor while keeping your roll-up intact.
Step 3: Add Cheese and Pepperoni
Evenly sprinkle shredded mozzarella cheese on top of the sauce, covering it well to create a gooey interior. Next, layer on the crispy pepperoni slices, ensuring each bite will be packed with flavor. The combination of cheese and pepperoni is what makes these roll-ups so irresistible!
Step 4: Season for Flavor
Sprinkle a dash of Italian seasoning and garlic powder over the cheese and pepperoni for an extra punch of flavor. This step is crucial as it elevates your Cheesy Pepperoni Pizza Roll-Ups and brings out the delectable Italian notes, making each bite a delightful experience.
Step 5: Roll It Up
Carefully roll the tortilla tightly from one end to the other, making sure all the delicious fillings are securely wrapped inside. This compact roll is what gives these pizza roll-ups their satisfying bite and hearty texture.
Step 6: Place on Baking Sheet
Place the rolled tortilla seam-side down on your prepared baking sheet. This will help keep the roll-ups together as they bake, allowing them to achieve that perfect golden-brown crust. Repeat the process for the remaining tortillas and filling ingredients until everything is assembled.
Step 7: Bake to Perfection
Pop the baking sheet in the oven and bake the roll-ups for 12-15 minutes. Keep an eye on them; they should be golden brown and the cheese bubbling away. This is when the aroma will fill your kitchen, making it hard to resist!
Step 8: Cool and Slice
Once baked, carefully remove the roll-ups from the oven and let them cool for a few minutes. This cooling period allows the cheese to set a bit, making them easier to slice. Use a sharp knife to cut them into bite-sized pieces, perfect for sharing.
Step 9: Serve and Enjoy
Transfer the sliced Cheesy Pepperoni Pizza Roll-Ups to a platter and serve them warm. They are delightful on their own or paired with your favorite dipping sauces, like marinara or ranch. These roll-ups are sure to be a hit at any gathering or as a quick snack!

Make Ahead Options
These Cheesy Pepperoni Pizza Roll-Ups are a fantastic choice for meal prep and can save you precious time during busy weeknights! You can assemble the roll-ups up to 24 hours in advance; simply prepare each roll, wrap them tightly in plastic wrap, and refrigerate. This keeps them fresh while allowing the flavors to meld beautifully. When you’re ready to serve, just pop them directly into a preheated oven at 375°F (190°C) for about 15-18 minutes until they’re golden brown and the cheese is melted. Covering with foil for the first half of baking helps retain moisture, ensuring they come out just as delicious as freshly made!
Cheesy Pepperoni Pizza Roll-Ups Variations
Feel free to get creative with these Cheesy Pepperoni Pizza Roll-Ups—there’s a whole world of delicious possibilities waiting for you!
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Spicy Twist: Use spicy pepperoni or add jalapeños for a kick of heat that elevates your roll-ups to new flavor heights. A little spice can make everything nice!
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Veggie Lover’s Delight: Incorporate sliced bell peppers, mushrooms, or olives for a burst of freshness and added nutrition. It’s a great way to sneak in some extra veggies!
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Dairy-Free Option: Swap mozzarella for a creamy dairy-free cheese alternative to make these roll-ups vegan-friendly without sacrificing that cheesy goodness. Everyone can enjoy this tasty treat!
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BBQ Flavor: Substitute tomato sauce with your favorite BBQ sauce for a sweet and smoky flavor twist. This can transform each roll-up into a delightful experience that’s hard to resist!
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Meat Lovers: Go beyond traditional pepperoni by adding cooked sausage, crispy bacon, or even ham. This hearty variation will surely satisfy any meat cravings.
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Pesto Perfection: Spread a thin layer of pesto on the tortilla before adding cheese and toppings. This lends an aromatic punch and a burst of Italian herb flavor that elevates the roll-ups.
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Flaky Pastry Style: For a different texture, try rolling the ingredients in puff pastry instead of tortillas. Bake until golden for a flaky, gourmet touch that impresses at any gathering.
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Mediterranean Vibes: Add feta cheese, sun-dried tomatoes, and spinach for a refreshing Mediterranean twist. Every bite will transport you to sunny shores!
For delightful suggestions on creative fillings, you can also explore options in these recipes: Pepperoni Pizza Bombs and Cheesy Bolognese Gnocchi for more tasty ideas!
How to Store and Freeze Cheesy Pepperoni Pizza Roll-Ups
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Fridge: Store any leftover Cheesy Pepperoni Pizza Roll-Ups in an airtight container in the refrigerator for up to 3 days to maintain freshness.
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Freezer: For longer storage, wrap the roll-ups tightly in plastic wrap and place them in a freezer-safe bag. They can be frozen for up to 3 months.
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Reheating: To reheat, bake the frozen roll-ups directly from the freezer at 375°F (190°C) for 15-20 minutes until heated through. You can also microwave them for a quick option, but they may not be as crispy.
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Make-Ahead Tips: Assemble your roll-ups in advance and refrigerate until ready to bake, making them a convenient option for quick meals or snacks.
Expert Tips for Cheesy Pepperoni Pizza Roll-Ups
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Tortilla Flexibility: Ensure tortillas are pliable to avoid cracks during rolling; warm them slightly in the microwave if needed.
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Add a Crunch: For a crispier finish, brush the roll-ups with olive oil or melt a little butter over them before baking.
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Cheese Distribution: Evenly distribute cheese and toppings for a balanced flavor; avoid overstuffing, which can lead to messy roll-ups.
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Flavor Boost: Experiment with different sauce varieties to change things up; homemade marinara or pesto can take your Cheesy Pepperoni Pizza Roll-Ups to another level.
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Make Ahead: Assemble your roll-ups in advance and refrigerate them; they can also be frozen for later use. Just reheat directly from frozen!
What to Serve with Cheesy Pepperoni Pizza Roll-Ups
Delight in creating a full meal around these tasty, low-carb snacks that will please everyone at your table.
- Fresh Garden Salad: Crisp and refreshing, a simple salad with mixed greens and vinaigrette brightens your meal and balances the cheesy richness.
- Creamy Garlic Dip: Perfect for dipping, this creamy concoction elevates each bite, adding a smooth texture that complements the crispy roll-ups beautifully.
- Roasted Veggies: A medley of roasted bell peppers, zucchini, and onions adds color, nutrition, and an earthy flavor that pairs wonderfully with the savory roll-ups.
- Zesty Marinara Sauce: A classic pairing, this homemade or store-bought sauce shines when served on the side for dipping and adds a touch of warm nostalgia.
- Sparkling Lemonade: The bright and effervescent flavors of lemonade contrast nicely with the richness of the roll-ups, offering a refreshing sip with each bite.
- Stuffed Mushrooms: Filled with herbs and cheese, these appetizers introduce umami and a delightful variation in texture that works beautifully alongside the roll-ups.
Each of these choices enhances the fun of your meal, making every bite a celebration of flavors!

Cheesy Pepperoni Pizza Roll-Ups Recipe FAQs
What kind of tortillas should I use for the roll-ups?
I recommend using low-carb tortillas as they provide the best structure for these Cheesy Pepperoni Pizza Roll-Ups. If you’re going for a keto option, look for keto-friendly wraps that are pliable and sturdy. You can also try whole wheat or cauliflower tortillas for a different twist!
How long can I store leftover roll-ups in the fridge?
Absolutely! You can store leftover Cheesy Pepperoni Pizza Roll-Ups in an airtight container in the refrigerator for up to 3 days. Just make sure they are well-sealed to retain their deliciousness and keep them from drying out.
Can I freeze the roll-ups?
Yes, indeed! To freeze your Cheesy Pepperoni Pizza Roll-Ups, wrap each roll in plastic wrap and then place them in a freezer-safe bag or container. They can be stored in the freezer for up to 3 months. When you’re ready to enjoy them, simply bake them straight from the freezer at 375°F (190°C) for 15-20 minutes or until heated through.
What are some common troubleshooting tips for making roll-ups?
If your roll-ups are cracking while you’re rolling them, it’s usually because the tortillas aren’t pliable enough. Try warming them slightly in the microwave for about 10-15 seconds to make them more flexible. Additionally, ensure you don’t overstuff them, as this can lead to messy roll-ups that may not hold together well!
Can I make these roll-ups healthier or cater to dietary needs?
Certainly! You can customize your Cheesy Pepperoni Pizza Roll-Ups by using dairy-free cheese for a vegan option or swapping out the pepperoni for turkey or chicken slices to reduce calories. If anyone has specific allergies, be sure to check the ingredients of sauces and tortillas to make sure they’re safe for everyone.
How can I enhance the flavor of my roll-ups?
For an extra boost of flavor, sprinkle some fresh herbs like basil or oregano over your fillings before rolling. You could also try different sauces, such as pesto, barbecue, or homemade marinara, to get that delightful taste you crave. Experimenting with toppings like olives or diced bell peppers can elevate your roll-ups even further!

Cheesy Pepperoni Pizza Roll-Ups for Easy Low-Carb Snacking
Ingredients
Equipment
Method
- Start by preheating your oven to 375°F (190°C). Line a baking sheet with parchment paper.
- Lay out a low-carb tortilla on a clean surface and spread a layer of tomato sauce over it.
- Sprinkle shredded mozzarella cheese on top of the sauce and layer on pepperoni slices.
- Sprinkle Italian seasoning and garlic powder over the cheese and pepperoni.
- Carefully roll the tortilla tightly from one end to the other.
- Place the rolled tortilla seam-side down on the baking sheet.
- Bake for 12-15 minutes until golden brown and the cheese is bubbling.
- Let the roll-ups cool for a few minutes before slicing into bite-sized pieces.
- Serve the sliced roll-ups warm, paired with dipping sauces like marinara or ranch.

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