Preheat your oven to 400°F (200°C).

In a large skillet over medium heat, cook the ground beef and chopped onion for about 6-8 minutes until browned. Drain excess fat.

Season the meat and onion mixture with salt, black pepper, garlic powder, and Worcestershire sauce. Stir well and cook on low for 2 minutes.

Grease a 9-inch pie dish with cooking spray or butter.

Spread the seasoned beef mixture evenly across the pie dish and top with shredded cheddar cheese.

In a mixing bowl, whisk together eggs, milk, and flour until smooth.

Pour the egg mixture over the beef and cheese layers.

Bake the pie for 25-30 minutes until golden brown and set in the center.

Let the pie cool for about 10 minutes before slicing and serving warm.